Pissing Teeth

New teeth grown from urine

Scientists have grown rudimentary teeth out of the most unlikely of sources, human urine. The results, published in Cell Regeneration Journal, showed that urine could be used as a source of stem cells that in turn could be grown into tiny tooth-like structures. The team from China hopes the technique could be developed into a way of replacing lost teeth.

Other stem cell researchers caution that that goal faces many challenges. [No, really?!] Teams of researchers around the world are looking for ways of growing new teeth to replace those lost with age and poor dental hygiene. [*]

The group at the Guangzhou Institutes of Biomedicine and Health used urine as the starting point. Cells which are normally passed from the body, such as those from the lining of the body’s waterworks, are harvested in the laboratory. These collected cells are then coaxed into becoming stem cells. A mix of these cells and other material from a mouse was implanted into the animals.

20130730-181513.jpg
It’ll mean a whole new routine in the morning…

The researchers said that after three weeks the bundle of cells started to resemble a tooth: “The tooth-like structure contained dental pulp, dentin, enamel space and enamel organ.” However, the “teeth” were not as hard as natural teeth.

This piece of research is not immediately going to lead to new options for the dentist, but the researchers say it could lead to further studies towards “the final dream of total regeneration of human teeth for clinical therapy”.

Prof. Chris Mason, a stem cell scientist at University College London, said urine was a poor starting point. “It is probably one of the worst sources, there are very few cells in the first place and the efficiency of turning them into stem cells is very low. You just wouldn’t do it in this way.” He also warned that the risk of contamination, such as through bacteria, was much higher than with other sources of cells. Prof. Mason added: “The big challenge here is the teeth have got a pulp with nerve and blood vessels which have to make sure they integrate to get permanent teeth.”

Source: BBC News

[*] Or, as someone who takes immunosuppressants which destroy teeth, this could be useful for people who take immunosuppressants…

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s